Research has been an integral part of the business of SA Pathology since its inception.
The close interaction between research and diagnostic pathology has led to implementation of many innovative tests that have now become routine.
SA Pathology attracts scientists of the highest calibre and has been internationally recognised across many scientific disciplines.
The role of SA Pathology as a pathology service and research hub is of direct benefit to the South Australian community. Public feedback from our patients and the general population shows that they understand, appreciate and actively support this endeavour.
If you would like to support this important work please contact the Royal Adelaide Hospital Research Fund who can assist with donation options.
Phone (08) 8222 5281 or by email RAHresearchfund@health.sa.gov.au
SA Pathology and its research partners investigate many forms of cancers, immune and genetic disorders, infectious, lung and endocrine diseases, transplant treatments, burn therapies, spinal, joint and bone conditions, and advances in neuropathology and microbiology.
Our researchers have achieved funding to conduct fundamental and translational research in world-class facilities within SA Pathology and its dedicated research arms, the Hanson Institute and the Centre for Cancer Biology.
The work of these bodies, in partnership with clinicians at hospitals and medical schools, enables clinical trials which evolve into new therapies and improved patient care.
SA Pathology actively fosters research and its translation into diagnostic testing. The fields of genetic and molecular pathology and cell imaging are areas where significant advances are being made in personalised medicine through innovative technology.
Access to sophisticated instrumentation and expert personnel allows us to develop more targeted tests, effectively cutting the number of tests sent to external providers and maximizing efficiencies to reduce costs for the health sector.
SA Pathology’s research and partnerships give it a distinct edge as a public pathology provider and positions us at the forefront of diagnostic testing.
The strength of SA Pathology’s partnerships defines and underpins our vital work in supporting the public health sector and serving the South Australian community.
Some of the research activities SA Pathology is currently associated with include:
Cytokine Receptor LaboratoryProf Angel Lopez
The laboratory seeks to understand the mechanism of cytokine receptor activation, contributing to the development of new drugs for conditions including leukaemia, asthma and arthritis.
Molecular Pathology ResearchProf Hamish Scott
This laboratory investigates transcriptional mechanisms and molecular pathogenesis in autoimmunity and haematological malignancies, including identification of disease-causing genes and mutations.
Molecular RegulationProf Sharad Kumar
This group’s research focuses on the cellular and molecular biology of disease, with an emphasis on cancer biology.
Acute Leukaemia LaboratoryA/Prof Ian Lewis and Prof Richard D’Andrea
The major focus is to understand mechanisms in normal blood cell growth and changes associated with myeloid diseases, in particular acute myeloid leukaemia (AML) and myeloproliferative disease (MPD).
Gastroenterology Research LaboratoryA/Prof Andrew Ruszkiewicz
Research activities include gastroenterology pathology, cancer precursor lesions and malignancies of the colorectum, oesophagus and pancreas.
Gene Regulation LaboratoryProf Greg Goodall
This laboratory focuses on micro RNAs which control epithelial to mesenchymal transition (EMT), a key step in cancer metastasis, which is the major cause of death from cancer.
Molecular SignallingProf Stuart Pitson
This team examines sphingolipid-mediated cell signalling pathways, and how they contribute to cancer and other diseases.
Neurovascular ResearchDr Quenten Schwarz
This research focusses on understanding signalling pathways in neuronal development.
Paediatric ImmunopathologyProf Tony Ferrante
This research unit studies immunological responses to allergies and Type 1 diabetes in young children including the identification of biomarkers for those at risk of developing these diseases.
Vascular Biology and Cell TraffickingA/Prof Claudine Bonder
A major focus is to investigate blood in normal and diseased states and identify markers that define a purified population of cells with a genetic profile which regulates differentiation and survival.
Mast Cell LaboratoryA/Prof Michele Grimbaldeston
This team researches mast cells as active participants in the allergic response.